Monday 9 december : Researching: New Study Finds Effective Clinical Treatment For Unexplained Recurrent Miscarriages

I found this article , I though it was interesting , may be my next step . I went to their website and  is extremely  expensive .. :-( 

http://www.colocrm.com/Services/ComprehensiveChromosomeScreening.aspx

New Study Finds Effective Clinical Treatment For Unexplained Recurrent Miscarriagesl

http://www.prnewswire.com/news-releases/new-study-finds-effective-clinical-treatment-for-unexplained-recurrent-miscarriages-175379941.html

DENVER, Oct. 23, 2012 /PRNewswire/ -- A recent study by the Colorado Center for Reproductive Medicine (CCRM) has found that a new technique that examines all 23 pairs of chromosomes in a human blastocyst (day five embryo), known as comprehensive chromosome screening (CCS), is an effective clinical treatment for unexplained recurrent miscarriages.

Miscarriage is a relatively common occurrence affecting roughly one in five pregnancies. However, only one to two percent of reproductive-aged women will have three or more consecutive, spontaneous miscarriages. The cause of recurrent miscarriage is complex in nature and can vary from autoimmune disorders to uterine abnormalities. For 50 percent of couples, recurrent miscarriages have no identifiable cause.

"Recurrent miscarriage is one of the most devastating experiences a couple can face," says William Schoolcraft, M.D., medical director of CCRM. "Our latest study offers hope to couples who previously had no where to turn. Comprehensive chromosome screening appears to greatly increase the odds of having a live birth."

It is well known that aneupliod embryos (chromosomally abnormal) will typically result in spontaneous miscarriage. CCRM clinicians recently conducted a study employing CCS and cryopreservation techniques, which allows them to select and transfer only blastocysts that have 23 pairs of chromosomes in a frozen embryo transfer. Study details and findings include:

• 42 women (36.7 mean age) with recurrent miscarriage (at least three proven miscarriages where fetal heartbeat was shown) had in vitro fertilization (IVF) with CCS.

• Nine patients had all aneuploid embryos; therefore, transfers could not be performed.

• Out of 33 patients who had at least one euploid (chromosomally normal) embryo transferred, 87.9 percent had clinical pregnancy; only one pregnancy resulted in a miscarriage.

• All the pregnancies have either resulted in a healthy delivery or are past mid-gestation and the potential live birth rate is 84.8 percent.

"Our two beautiful boys would not exist without the CCS technology at CCRM," says CCRM patient Kristin Scott Pardini. "After three devastating miscarriages we tried IVF with CCS. We had two egg retrievals resulting in a total of 41 eggs. Only one egg produced an embryo that had the necessary 23 chromosome pairs. That one embryo became our first son, Roman, who is now three."

Mandy Katz-Jaffe, PhD, director of research for CCRM added, "Until now, there was thought to be no effective clinical treatment for unexplained recurrent miscarriage, but now we have evidence that CCS can improve the ability to have a successful pregnancy. This is an exciting discovery that will open doors for many couples wanting to have children."

About the Colorado Center for Reproductive MedicineFounded in 1987 by Dr. William Schoolcraft, the Colorado Center for Reproductive Medicine is one of the nation's leading infertility treatment centers, providing a wide spectrum of infertility treatments ranging from basic infertility care to advanced in vitro fertilization (IVF) technology. Today, joined by Drs. Eric Surrey, Debra Minjarez, Robert Gustofson and Jennifer Brown, Dr. Schoolcraft and his staff achieve some of the highest pregnancy rates in the country. CCRM has been ranked "The #1 Fertility Center in the U.S., with the Greatest Chance of Success" by Child.com. For more information, visit www.ColoCRM.com.

SOURCE Colorado Center for Reproductive Medicine

RELATED LINKS
http://www.colocrm.com

Unexplained Recurrent Miscarriages : Baby number 5

Hello Everybody,
My name is  Johanna  and everybody calls me YoYo.  I am a spanish speaking  girl  living in Australia 7 years ago , so please I apologise in advance If my  English  is not the best .
Today is my  first post  ever.
My purpose with this blog is telling you my story, and may be help you  to find  the answers you need  to overcome  your current situation or just to let you know that  you are not the only one , I was there too  and many other women  were  and are there too . This blog  is my way of looking  for  healing for myself , healing through  expressing what for years I have been never been able to  properly talk with anyone.
This is my way to reach that like me  have a history of  ”unexplained recurrent/repetitive  miscarriages”.
I am 33 years old ,  and I have been pregnant 5  times .
As a matter of fact  I am currently pregnant  I supposed to be 8 weeks  or more  but my last ultrasound  1 week ago  shows  5 week 4 days  embryo ,  heartbeat:  59 Bpm,  they found  fetal pole too .
About 3 weeks  ago , the embryo  seems to be  6 weeks 2 days,   they found  heartbeat:  47 Bpm  consistent with a bradycardia  (very low heart beat) The radiologist  advised nothing to worry about as it might be that babies heart Just start  Beating  .
Even though  I am freaking out , a  heartbeat , was the last request from the doctor at  the hospital  , before  he would authorise to give me  the  prescription for Clexane .  Clexane  is one of the drugs I am currently using to prevent   my body of producing  clots.  Was very difficult  to convince  my doctor  at the hospital in Australia l to  prescribe it.

The doctors at the Townsville hospital  consider that Protein S deficiency   was not low enough as to  prescribe  the Clexane . ( my results were 47 , normal ranges start at 59 )   I am also  a low positive for the Anticardiolipin antibodies, for which they send me to take  baby aspirin  and folic acid .
So today  Monday 2 of December of 2014 ,  at 4 pm  I got  to visit the “North  Xray ” for another ultrasound .  Is currently  8.46 am , I have  a Psychologist appointment  ( thanks for the mental health  government fund for this )  and then  I have to wait to   see the results in this ultrasound .
I had  1 ultrasound last week  at the hospital that shows basically nothing   but the heartbeat , and one previous that one 3 weeks ago that shows  the most beautiful thing I  ever saw in my life    That day I couldn’t  believe what my eyes were looking   I had 5 previous pregnancies , the 2 last ones , blighted ovum . But  in this one , a little embryo  develop  was  amazing , tears were falling from my eyes  .